How Omega-3 versus Omega-6 fatty acids?

Omega-3 (ω-3) and omega-6 (ω-6) polyunsaturated fatty acids (PUFAs) are desirable components of oils with special dietary and functional properties.

Their therapeutic and health-promoting effects have already been established in various chronic inflammatory and autoimmune diseases through various mechanisms including :

1. Modifications in cell membrane lipid composition
2. Gene expression
3. Cellular metabolism
4. Signal transduction

Omega 3 fatty acids possess strong anti-inflammatory properties which lower risk of

1. Heart disease
2. Alzheimer’s
3. Promotes vision
4. Boost brain health

The application of ω-3 and ω-6 PUFAs in most common skin diseases has been examined in numerous studies, but their results and conclusions were mostly opposing and inconclusive.

It seems that combined ω-6, gamma-linolenic acid (GLA), and ω-3 long-chain PUFAs supplementation exhibits the highest potential in diminishing inflammatory processes, which could be beneficial for the management of inflammatory skin diseases, such as

1. Atopic dermatitis
2. Psoriasis
3. Acne

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