Major Depressive Disorder.

A mental health disorder characterised by persistently depressed mood or loss of interest in activities, causing significant impairment in daily life.

The persistent feeling of sadness or loss of interest that characterises major depression can lead to a range of behavioural and physical symptoms.

These may include changes in

• sleep, appetite, energy level, concentration, daily behaviour or self-esteem.
• Depression can also be associated with thoughts of suicide.

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